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MPN&MPNr-EuroNet



about MPN&MPNr-EuroNet


Chair

Dr. Sylvie HERMOUET

Laboratoire d'Hématologie
Institut de Biologie
CRCINA, Inserm U1232
Institut de Recherche en Santé 2 (IRS-2)
22 Boulevard Benoni Goullin
44200 Nantes
France


Local Organizer



Institute for Medical Research
University of Belgrade, Serbia



Serbian Academy of Medical Sciences

Meeting Temporary Programme

Pathogenesis, diagnosis and therapy
of myeloproliferative neoplasm

WEDNESDAY May 8th, 2019

 
17:30 - 18:00 Registration Sylvie Hermouet (FR)
Vladan Čokić (RS)
18:00 - 18:15 Welcome and Schedule
18:15 - 19:30 Special session: Pathogenesis and therapy of MPN Chair: François Girodon (FR)
18:50 - 19:00 Origin and clonal evolution of myeloprofiferative neoplasms Radek Skoda (CH)
19:00 - 19:30 Impact of Interferon on the therapeutic approach of MPN François Girodon (FR)
 
20:00 Welcome Dinner
 

THURSDAY May 9th, 2019

 
08:30 - 10:30 WG1/2 session: Detection, Validation
and Quantification of MPN mutations
Chair: Julia Asp (SE)
08:30 - 09:00 Clinical relevance of additional mutations in MPN in a Swedish cohort Julia Asp (SE)
09:00 - 09:30 Title to be announced Naomi Porret (CH)
09:30 - 10:00 Multiple variants defining the genetic predisposition
to BCR-ABL-negative myeloproliferative neoplasms
Adrian Trifa (RO)
10:00 - 10:05 Discussion
10:05 - 10:15 Short communication from abstract selection
10:15 - 10:25 Short communication from abstract selection
 
10:25 - 10:50 Coffee/tea break
 
10:50 - 12:40 Special Session: New Advances in Treatment of MPNs Chair: Andrija Bogdanovic (RS)
10:50 - 11:20 Transplantation Algorithm for Myelofibrosis in 2019 Donal McLornan (UK)
11:20 - 11:50 Disease classification and personalised prognosis in MPNs Jyoti Nangalia (UK)
11:50 - 12:10 Current medical treatment of MPNs Andrija Bogdanovic (RS)
12:10 - 12:15 Discussion
12:15 - 12:25 Case Study
12:25 - 12:35 Short communication from abstract selection
 
12:40 - 14:10 Lunch and Free Time for Networking and Poster Session
 
14:10 - 16:30 WG3 session: Hereditary Erythrocytosis and Thrombocytosis Chair: Mary Frances McMullin (UK)
14:10 - 14:40 Diagnostic pathways in erythrocytosis Mary Frances McMullin (UK)
14:40 - 15:10 Molecular diagnosis of idiopathic erythrocytosis:
a French experience
François Girodon (FR)
15:10 - 15:40 Novel Insights on Molecular Characterization
of Congenital Erythrocytosis
Celeste Bento (PT)
15:40 - 15:45 Discussion
15:45 - 15:55 Short communication from abstract selection
 
15:55 - 16:20 Coffee/tea break
 
16:20 - 17:30 Special Session: Technological Advances Chair: Vladan Čokić (RS)
16:20 - 17:05 CRISPR-based Gene Editing: Concepts & Applications & Functional Rescue of a Novel Mpl Mutant in Primary HSPCs using Gene Editing Cédric Cleyrat (USA)
17:05 - 17:15 Effect of JAK2V617F on cytokine production in CRISPR- enginereed UT-7 cells Sylvie Hermouet (FR)
17:15 - 17:20 Discussion
17:20 - 17:30 Short communication from abstract selection
 
20:00 Gala Dinner
 

FRIDAY May 10th, 2019

 
09:00 - 11:00 Special Session: Inflammation in MPNs Chair: Sylvie Hermouet (FR)
09:00 - 09:45 Inflammation as a driver of clonal evolution
in myeloproliferative neoplasm
Angela G. Fleischman (USA)
09:45 - 10:15 HSP and inflammation cytokines in MPNs Sylvie Hermouet (FR)
10:15 - 10:45 Inflammation mediated development of fibrosis in MPN Vladan Čokić (RS)
10:45 - 10:50 Discussion
10:50 - 11:00 Short communication from abstract selection
11:00 - 11:10 Short communication from abstract selection
 
11:10 - 11:40 Coffee/tea break
 
11:40 - 12:30 General business session Chairs: Sylvie Hermouet (FR)
 
12:30 - 13:30 Lunch
 
13:30 - 15:00 Sightseeing of Belgrade
15:00 Meeting Adjourn - Good bye